A healthy and efficient immune system depends on a complex balance of reactions. Certain circumstances may lead to an imbalance in these reactions resulting in a loss of mobility, stiff joints and a drop in energy levels. Type II collagen that is present in Ortho UCII is obtained via a unique patented low-temperature procedure that guarantees a high level of quality. Thanks to this special production method it is possible to obtain type II collagen with its original triple helical structure with epitopes intact. Otho UCII may only be used alone or in combination with or as a complement to Procartil 900 or Harpagocartil.